Year: 2017 | Month: December | Volume 6 | Issue 2
HIV Presenting as Cerebellar Ataxia
Abstract:
Cerebellar disorders associated with HIV infection are typically the result of discrete cerebellar lesions resulting from opportunistic infections such as toxoplasmosis and progressive multifocal leukoencephalopathy or primary CNS lymphoma. Clinical symptoms and pathologic abnormalities related to the cerebellum may also be observed with HIV dementia. A primary cerebellar degeneration with HIV is rare. In our case the patient presented with progressively unsteady gait, slurred speech, and limb clumsiness. Examination revealed gait ataxia, impaired limb coordination, dysarthria, and abnormal eye movements. CD4 lymphocyte counts was very low 26 cells/mm3. Neuroimaging studies showed prominent cerebellar atrophy. We report a syndrome of unexplained, isolated degeneration of the cerebellum occurring in association with HIV infection.
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